Research Output

Validation of our platforms through excellent preclinical and clinical research

Information is being updated...
  • Solid immunomodulatory potential in peripheral blood mononuclear cell co-culture, indicating that it can regulate and modulate immune responses;

Platform Extensive in vitro characterization:
In vitro
  • High yields and viability indicate it is a robust and reliable cell source;

  • Mesenchymal stem cell markers, and lack of HLA, suggest they are immunocompatible;

  • The lack of senescence indicates a young cell population with good proliferative capacity;

  • Karyotype is stable, indicating that the product does not exhibit chromosomal abnormalities.

  • Displayed marked improvement in gross changes of OA, such as cartilage osteophytes and subchondral bone exposure;

Platform has shown promising results in managing osteoarthritis and synovitis by promoting tissue repair, reducing inflammation, and improving joint function:
Osteoarthritis and Synovitis
  • Reduced the formation of fissures on the surface of the femoral condyle, indicating better preservation of articular cartilage;

  • Decreased the expression of inflammatory markers in the treated group synovium, indicating suppressed inflammation.

  • Reduced inflammatory cytokines and chemokines in bronchoalveolar lavage (BAL) fluid, indicating suppressed lung inflammation;

Platform has demonstrated potential in managing Acute Respiratory Distress Syndrome (ARDS) by reducing inflammation, promoting lung repair, and preventing fibrosis by suppressing the activation of pro-inflammatory cytokines:
Acute Respiratory Distress Syndrome (ARDS)
  • Reduced protein concentration in lavage fluid, suggesting a decrease in lung edema and permeability;

  • A reduced number of neutrophils, macrophages, eosinophils, and basophils in BAL fluid, indicating reduced inflammation, prevention of lung tissue damage, and improved oxygenation;

  • Reduced structural alveolar damage, consolidation, and inflammation, indicating a more favorable environment for repair and regeneration;

  • Downregulated inflammatory gene expression of lung tissue, indicating a reduction in lung damage and promotion of repair.

  • Improved the survival rate of animals;

Platform has shown positive effects in managing acute kidney injury by improving survival rate, serum and urine biochemistry, and preventing structural chronic kidney injury:
Acute Kidney Injury
  • Promoted and sustained normal diuresis, indicating that the kidneys can produce and excrete urine at a regular rate;

  • Improved biochemistry and electrolyte balance in urine and serum, indicating a preserved kidney function;

  • Reduced inflammation and oxidative stress in the kidney, indicating prevention of acute kidney injury;

  • Reduced structural damage preventing tubular dilatation, acute tubular necrosis, cast formation, loss of brush border, interstitial fibrosis, and tubular atrophy indicates a long-term protective effect on the kidney structure.

  • We are working hard to ensure that we provide you with the most comprehensive information as soon as possible.

Platform has shown promising results in managing skin neutrophilic dermatosis by reducing inflammatory cytokine synthesis and promoting tissue repair:
Skin Neutrophilic Dermatosis