Research Products

A range of products that are essential tools designed for the development and testing of therapeutics

CELLS
EXTRACELLULAR VESICLES
CELL CULTURE MEDIA KITS

We manufacture extensively characterized GMP-like Cells for research, non-clinical applications

We provide readily available Extracellular Vesicles derived from placental mesenchymal stromal cells, ready for use in non-clinical applications

Our Cell Culture Media Kits contain basal media with supplement and are adapted to support the growth of Cells

ELEVATING RESEARCH TO REVOLUTIONARY CELL THERAPY

Our portfolio includes GMP-compliant and research-grade mesenchymal stromal (MSCs) and somatic (chondrocyte) cells suitable for preclinical research.

These cells have been produced with exceptional quality and efficacy parameters and tested in many preclinical studies.

FROM BENCH TO BREAKTHROUGHS

hPMSCs (subtypes)
QC Information

Type options: All subtypes

Culture options: FBS/ hPL

Culture conditions options: 2D/ 3D

Passage options: P0/ P1/ Custom

Shipping options: Cryopreserved/ Proliferating

Quantity options: 1M cells/vial / Custom

Quality options: GMP-like/ GMP

Human Placenta-derived Mesenchymal Stromal Cells (hPMSCs) exhibit the characteristic markers and functions of MSCs. As a result, they serve as a valuable model for investigating differentiation, inflammation, tissue homeostasis, and regeneration.

The placenta is a complex tissue formed from contributions from both maternal and fetal tissues, leading to a higher diversity of cell types.

KELI manufactures specialized subtypes of placental cells options: Placental Chorionic villi MSCs; Placental Decidua basalis MSCs; Placental Amniotic epithelial cells; Placental Amniotic MSCs; Chorionic plate trophoblast cells; Chorionic plate MSCs; Decidua NK-CD56+CD3-; Umbilical cord (whole) MSCs; Umbilical cord tissue MSCs; Umbilical cord Wharton jelly MSCs.

Culture conditions/

hPMSCs are qualified and tested for safety and quality per European Pharmacopeia

Placenta donor tests: HIV 1/2, HBsAg, anti-HBcor, anti-HCV, anti-HBs, and T. pallidum

Safety tests on hPMSCs: sterility, mycoplasma, and endotoxin

Phenotypic identity: FACS analysis

Potency evaluation: lymphocyte proliferation and anti-inflammatory assays

Stability and storage: liquid nitrogen maintains cell viability and functionality for no less than four years.

Shipping: worldwide delivery of cells and EVs

Mesenchymal Stromal Cells
CELLS

KELI has developed and produced cellular products for research organizations and internal non-clinical and clinical studies. This involvement includes handling tissue acquisition, cell upstream and downstream processes, large-scale bioreactor cultures, and quality control analysis. Our specialized knowledge allows us to optimize the conditions for different types of cells, ensuring consistent cellular quality. We are adept at establishing robust manufacturing processes and meeting stringent regulatory requirements.

Chondrocytes

Chondrocytes derived from humans serve as valuable in vitro models for investigating cartilage regeneration and repair, exploring the impacts of cytokines and growth factors on cartilage, examining specific gene regulation, and unraveling arthritis pathophysiology. KELI Therapeutics offers human chondrocytes isolated from healthy articular cartilage (hCHs) and osteoarthritic cartilage (hOACHs) from the knee of individual donors.

Product Information

hCHs and hOACHs are qualified and tested for safety and quality per European Pharmacopeia

Cartilage donor tests: HIV 1/2, HBsAg, anti-HBcor, anti-HCV, anti-HBs, and T. pallidum

Safety tests on hCH: sterility, mycoplasma, and endotoxin

Potency evaluation: COL2A1 expression analysis

Stability and storage: liquid nitrogen maintains cell viability and functionality for no less than four years.

Shipping: worldwide delivery of cells on dry ice

Downloads

Certificate of analysis (CoA) is available with order

(#CH-01) coming soon...

(#CH-01) coming soon...

#PSC-01 (example)

#PSC-01 (example)

Certificate of analysis (CoA) is available with order

hCHs, cryopreserved
Cat#: CH-01

Passage: One

Cells/vial: 500,000

hOACHs, cryopreserved
Cat#: CH-02

Passage: One

Cells/vial: 500,000

Safety Data Sheet (customised to the cell/ EVs subtype):

Product Data Sheet (customised to the cell/ EVs subtype):

(#CH-02) coming soon...

(#CH-02) coming soon...

Placental Chorionic villi MSCs

Cat#: PCV-MSC

Placental Decidua basalis MSCs

Cat#: PDB-MSC

Placental Amniotic epithelial cells

Cat#: PAE-MSC

Placental Amniotic MSCs

Cat#: PA-MSC

Chorionic plate trophoblast cells

Cat#: PCP-TC

Chorionic plate MSCs

Cat#: PCP-MSC

Decidua NK-CD56+CD3-

Cat#: PDB-NK

Umbilical cord (whole) MSCs

Cat#: UC-MSC

Umbilical cord tissue MSCs

Cat#: UCT-MS

Umbilical cord Wharton jelly MSCs

Cat#: UCWJ-MSC

Mesenchymal Stromal Cells Media Kit

The cell culture system supports in vitro expansion and differentiation of hPMSCs. A kit includes a Basal Medium and Supplement for a Complete Culture Medium formulation. Two versions are available: Basal media with serum-containing supplement (PL-CM) and basal media with exosomes-free supplement (PL-CM-EF).

Product Information
Kit Components:

Basal Media (PL-BM), 500 mL

Supplement (PL-SP), 50 mL

PL-CM

Cat#: KIT-01

PL-CM-EF

Cat#: KIT-02

Rigorous quality control tests ensure reliable and consistent product quality.

Safety tests on media lots: sterility, mycoplasma, and endotoxin

Growth promotion: supports the growth of GMP-grade hPMSCs and EVs collection

Shipping: worldwide delivery of media and supplement

Kit Components:

Basal Media (PL-BM), 500 mL

Supplement (PL-SP-EF), 50 mL

CELL CULTURE MEDIA KITS

KELI Therapeutics offers cell culture media and reagents for culturing primary cells — specialized cell culture media kits for human Placental Mesenchymal Stromal Cells and Chondrocytes.

Chondrocytes Media Kit

Chondrocytes Media Kit (CH-CM) is a complete medium designed for optimal growth of primary chondrocytes in vitro.

Product Information

Rigorous quality control tests ensure reliable and consistent product quality.

Safety tests on media lots: sterility, mycoplasma, and endotoxin

Growth promotion: supports the growth of GMP-grade human chondrocytes

Shipping: worldwide delivery of media and supplement

Downloads

(#KIT-03) coming soon...

(#KIT-03) coming soon...

Certificate of analysis (CoA) is available with order

Downloads

(#KIT-02) coming soon...

(#KIT-02) coming soon...

Certificate of analysis (CoA) is available with order

CH-CM

Cat#: KIT-03

Kit Components:

Basal Media (CH-BM), 500 mL

Supplement (CH-SP), 50 mL

EXTRACELLULAR VESICLES

Extracellular Vesicles (EVs) are collected and formulated from hPMSCs.

EVs play an essential role in cellular communication by transporting proteins, lipids, miRNAs, and mRNAs between cells. #EV-01 inhibits immune cells and contains molecules, reducing inflammation, and fibrosis and promoting tissue repair.

hPMSC EVs
Product Information
Downloads

Certificate of analysis (CoA) is available with order

10^9 EVs/100 µl, sterile

Cat#: EV-01

hPMSCs (a starting material for #EV-01) are qualified and tested for safety and quality per European Pharmacopeia

The method of preparation: tangential flow filtration

Safety tests: sterility, mycoplasma, and endotoxin

Phenotypic identity: FACS analysis

Potency evaluation: particle count, protein, and RNA concentrations. The cells' potency is assessed through various assays

Stability and storage: -80°C in the proprietary solution ensures EVs functionality for at least six months